Role of homocysteine metabolism in the development of endothelial dysfunction and hypertension in patients with multiple myeloma

The article is devoted to the modern understanding of endothelial dysfunction development, role hyperhomocysteinemia, and, as a consequence, hypertension in patients with multiple myeloma receiving multiagent chemotherapy. Considering that potential standard examination does not allow identifying subclinical dysfunction, using specific techniques necessary, particular, determine homocysteine level monitor function. aim this review was summarize current etiology and prospects for detecting early, changes, including myeloma. Assessment can be useful precisely cardiovascular disease order stratify risk developing events